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Cancer is a disease caused by a genetically diverse population resulting from acquisition of advantageous genetic mutations (driver mutations) by the cells of origin, followed by clonal selection.　Recent advances in next-generation sequencing (NGS) technology have unveiled genetic abnormalities associated with various cancers. However, many fundamental questions regarding their biological significance remain elusive. In our laboratory, we specialize in the study of cancers, including hematological malignancies, aiming to decipher their unknown pathogenesis. We employ mouse models and patient samples, integrating cutting-edge molecular biological techniques and omics data analyses. Our goal is to translate novel insights gained from basic research into clinical practice, thereby making significant contributions to the better disease management and ultimately improving public health.

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